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Liverpool vs Atletico Madrid Prediction 17.09.2025

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Liverpool vs Atletico Madrid Prediction 17.09.2025

Liverpool vs Atletico Madrid Prediction

Liverpool vs Atletico Madrid Prediction and Betting Tips sees the Reds hosting the Spanish side at Anfield on Wednesday. Liverpool have made a blistering start to the Premier League with four straight victories, all decided by late goals. The European stage, though, is a different beast. You can catch the latest Champions League Predictions from XpertStats tipsters for all the inside info.

  • Liverpool have won all four of their Premier League matches this season, each with late winners after the 83rd minute.
  • Atletico Madrid are known for their defensive resilience, keeping clean sheets in 42% of Champions League games under Diego Simeone.
  • Mohamed Salah has 44 Champions League goals and 17 assists, leading Liverpool’s European charge.
  • Head-to-head in normal time favors Liverpool with three wins and one draw from eight meetings against Atletico.


Liverpool’s season so far is a mix of brilliance and nail-biting finishes. Mohamed Salah continues to shoulder the burden, scoring in the 95th minute against Burnley to maintain Liverpool’s perfect start. Alexander Isak may finally make his debut, though a starting role is unlikely. With Curtis Jones still sidelined and Mac Allister under load management, Arne Slot could shuffle his midfield. Even so, the Reds’ home record in Europe is formidable, 14 consecutive home wins and 13 straight matches with at least two goals is a stat that demands attention.

Atletico Madrid, meanwhile, have had a rocky start in La Liga, only managing a first win in four attempts. Simeone’s side, famed for their defensive grit, may find Anfield an unforgiving venue, but history shows they are no pushovers. With a 42% clean sheet rate in UCL matches under Simeone and scoring in 15 of their last 16 group-stage matches, Atletico’s resilience could test Liverpool’s last-minute magic. Injuries remain a concern, particularly for Alvarez, Cardoso, Gimenez, Baena, and Almada, forcing tactical tweaks from the Argentine tactician.

The head-to-head story adds more intrigue. Liverpool won both group-stage encounters against Atletico in 2021-22, flipping the script on a team that initially led in historical meetings. Even so, Simeone has previously outfoxed Arne Slot in past clashes, suggesting the visitors won’t just roll over. Will Liverpool rely again on late drama, or can they secure an earlier decisive advantage this time around? It’s hard to say how this will end, but expectation and tension are off the charts at Anfield.

For betting enthusiasts, the clash hints at high tension and physicality. Considering both teams’ fighting spirit, an Over 20.5 fouls bet seems compelling. Liverpool’s last few matches have been scrappy, with Atletico historically packing games with tactical fouls. Expect a battle in midfield and defensive challenges aplenty. For those looking at alternative angles, Mohamed Salah’s goal involvements or a late-minute winner are also tempting betting avenues. Overall, this game promises drama, strategy, and all the unpredictable excitement of European nights.

Prediction
Over 20.5 Fouls @1.55
Physicality has always defined Atletico Madrid, and Liverpool have shown early-season grit that leads to fouls. With several key players returning from injury, Liverpool may rely on aggressive pressing to control the midfield. Atletico, historically adept at forcing opponents into errors, will likely employ fouls strategically to neutralize Liverpool’s attacking threats. In their previous encounters, both teams frequently breached the 20-foul mark, particularly in high-pressure European matches. The combination of Anfield’s electric atmosphere and the opening match intensity will likely escalate aggressive challenges. Given Liverpool’s late-goal tendencies and Atletico’s defensive resilience, the match could become scrappy, with repeated interruptions and tactical fouling. Considering historical stats, team styles, and the importance of early points in the Champions League group stage, over 20.5 fouls emerges as a credible betting angle. It balances both teams’ approach to physical duels with statistical precedent.

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Author

  • Alexandru Florin is a football betting expert, providing tips and accumulator predictions for xpertstats.com since 2022. With a strong focus on data-driven analysis, he delivers well-researched insights and reliable advice for bettors aiming for long-term profit.

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