AS Roma vs Midtjylland Prediction and Betting Tips for the UEFA Europa League clash, scheduled for November 27, 2025, at 17:45 GMT. The match will be broadcast live on TNT Sports 7 and Discovery+ from the iconic Stadio Olimpico in Rome. Roma’s pursuit of a record 100th Europa League win meets a Midtjylland team yet to drop a single point this season. In this article, you’ll find expert insight and analysis inspired by Europa League Predictions from XpertStats tipsters.

• AS Roma host Midtjylland at the Stadio Olimpico on Thursday, November 27, 2025.
• The Giallorossi aim to end the Danish side’s flawless European run.
• Midtjylland have scored in all their Europa League games so far.
• Roma are chasing their 100th Europa League victory in club history.

Roma come into this one riding a wave of confidence after three straight victories in all competitions, capped by a 3-1 win over Cremonese on Sunday. Matias Soule’s creativity, Evan Ferguson’s rediscovered form, and Pellegrini’s leadership have brought the spark back to Gian Piero Gasperini’s side. Yet, in Europe, things haven’t been as smooth. Two home defeats in the Europa League have dented their campaign, and history looms large, Roma have never lost three European home games in a row. Can they really afford to make that bit of history now? Probably not. The pressure is heavy, and the Olimpico crowd will expect a statement.

Midtjylland, meanwhile, arrive in Rome like a storm that hasn’t slowed down. Four games, four wins, and 11 goals scored, the Wolves have been ruthless. From set pieces to counterattacks, Mike Tullberg’s side have found ways to punish every opponent. The 3-1 win against Celtic earlier this month showcased their versatility, with Franculino once again proving lethal in front of goal. Still, their recent 2-1 domestic defeat to Sonderjyske was a reminder that perfection doesn’t last forever. Maybe this trip to Italy is where that run ends or maybe it’s where they prove everyone wrong again.

Team news could play a big part. Roma will likely miss Paulo Dybala and Leon Bailey, though both could make late bench appearances. Angelino and Dovbyk remain sidelined, leaving Ferguson to lead the line once more. Midtjylland have their own headaches, with goalkeeper Ovie Ejeheri and winger Edward Chilufya both doubtful. That’s a bold test of depth for a team built more on cohesion than star power. Even so, it’s hard to underestimate their discipline and belief right now.

This feels like a match balanced on a knife’s edge. Roma’s attacking flair against Midtjylland’s fearless efficiency, it’s the kind of clash that defines group-stage drama. A draw wouldn’t shock anyone, but Roma’s quality at home, driven by the hunger for that 100th Europa League victory, might just tip the scales. It’s hard to say how this will end, but one thing’s sure: it won’t be dull. For more Europa League Predictions, keep following XpertStats for up-to-date insights and data-backed tips.