Napoli vs Eintracht Frankfurt Prediction and Betting Tips for Matchday 4 of the Champions League, scheduled for Tuesday, November 4, 2025, at 17:45 GMT. The clash at the Stadio Diego Maradona will be broadcast live on Amazon Prime and Discovery+. Both teams are desperate to recover from humiliating defeats last time out, and goals seem almost inevitable. For more insights and expert picks, explore our Champions League Predictions on XpertStats.

• Napoli and Frankfurt both suffered heavy defeats in their previous European outings.
• Napoli remain unbeaten at home this season, with only one loss in their last 18 UCL matches at the Maradona.
• Frankfurt have conceded 25 goals in their last eight games but still score freely.
• Over 2.5 goals has landed in all of Frankfurt’s Champions League fixtures this season.

Napoli have been unpredictable lately. After a 6-2 thrashing by PSV, Antonio Conte’s men clawed back some pride in Serie A, beating Inter Milan and Lecce to reclaim top spot. Still, a goalless draw with Como showed that the Maradona fortress can wobble. Milinkovic-Savic’s penalty saves have rescued them more than once this season, but Napoli’s real weapon lies in attack, Hojlund’s return from injury could reignite the firepower they desperately need. Can they finally find the balance between dominance and discipline?

Even with all their issues, Napoli’s home record remains a rock. Just one defeat in 18 Champions League home games is nothing to sneeze at. They thrive on the Maradona crowd’s roar, and Conte knows this match could define their group stage fate. His problem? Keeping 11 men on the field. Two red cards in three games have cost them dearly. Still, with Anguissa’s recent scoring form and Politano’s pace on the wing, there’s every reason to believe they’ll come out swinging.

On the other side, Frankfurt are in a funk. Dino Toppmöller’s side have gone from Bundesliga joy to European misery. Back-to-back 5-1 defeats to Atletico and Liverpool were brutal, exposing a leaky defense and a crisis of confidence. Yet, they’re never boring. They’ve scored in 13 of their 14 games this season and boast Fares Chaibi, currently topping the Bundesliga assists chart. It’s that creative spark that keeps them dangerous, no matter how chaotic their back line looks.

Can Frankfurt turn that chaos into something constructive? Hard to say. But there’s always a sense that they could explode at any moment. Mario Götze might be past his prime, but his vision could open doors for Burkardt, who’s in fine scoring form. That said, facing Napoli in their own den is another story entirely. Expect goals, mistakes, and plenty of emotion, just the kind of match that makes football beautiful. For more bold calls like this, check our latest Champions League Predictions from XpertStats.