Dortmund vs Athletic Bilbao Prediction and Betting Tips for Wednesday’s UEFA Champions League group-stage clash at Signal Iduna Park. Both clubs are still chasing their first European win of the season, and the stakes couldn’t be higher. In this article, you’ll discover Champions League Predictions from XpertStats analysts, including insights into form, injuries, and key storylines.

• Dortmund unbeaten in all competitions this season, coming off a 2-0 Bundesliga win
• Athletic Bilbao struggling with form after three straight La Liga defeats
• Guirassy and Adeyemi expected to lead the line for Dortmund
• Injury doubts remain over Nico Williams for Athletic Bilbao

Dortmund’s European opener was a rollercoaster a 4-4 draw in Turin against Juventus that fans won’t forget anytime soon. BVB actually led 4-2 heading into injury time, only to concede twice in a chaotic finale. Still, Niko Kovac’s men have shown impressive consistency, sitting second in the Bundesliga with four wins from five. A 2-0 victory over Mainz on Saturday kept momentum strong. The atmosphere at Signal Iduna Park is usually electric on Champions League nights, and Dortmund will be desperate to turn that into three points.

It’s not all perfect, of course. Injuries to Emre Can and Julien Duranville hurt midfield depth, and Serhou Guirassy’s late withdrawal against Mainz raised a few eyebrows. But the Guinean striker, with five goals already this season, is expected to return. Alongside Karim Adeyemi, who’s chipped in with three goals and two assists, Dortmund’s attack looks sharp enough to trouble any defense. Can they finally get over their recent struggles against Spanish sides? That’s the big question.

Athletic Bilbao, meanwhile, arrive in Germany short on confidence. Ernesto Valverde’s side have lost three of their last four league matches, including a frustrating 1-0 defeat to Villarreal last weekend. The Basques kicked off their Champions League return with a 2-0 home loss to Arsenal, so they badly need a result here. They’ve been resilient against German opposition in the past, but recent form suggests this will be a tough ask.

Fitness worries add to the challenge. Nico Williams remains a doubt, while Alex Berenguer and Mikel Vesga are sidelined. Without Williams, Athletic lose much of their spark in attack, leaving Gorka Guruzeta to shoulder responsibility. The Lions were Europa League semi-finalists last season, but this step up has already shown its bite. Valverde knows a point in Dortmund would feel like a small victory, though history tells us nothing comes easy at the Westfalenstadion. If Bilbao are to shock the odds, they’ll need discipline, grit, and maybe a slice of luck.

Looking at the bigger picture, both sides are under pressure. Dortmund’s home record in Europe is formidable, but Athletic are stubborn opponents who won’t roll over easily. That said, with confidence high and attacking options clicking, Dortmund appear to hold the upper hand. This one could be lively, and it might just set the tone for the rest of the group stage. Expect fireworks under the lights on Wednesday night in Dortmund, where only one team looks ready to seize the moment in this crucial clash of the Champions League Predictions.