Liverpool vs Real Madrid Prediction and Betting Tips for Matchday 4 of the Champions League, scheduled for Tuesday, November 4, 2025, at 20:00 GMT. The match unfolds at Anfield and will be broadcast live on Amazon Prime and BBC Radio 5. These two sides have made a habit of meeting deep into the tournament, and this one promises drama again. Expect high intensity, goals, and moments that will live long in memory. Check out Champions League Stats for deeper insights and historical data on these European powerhouses.

• Liverpool look to repeat last season’s home win over Real Madrid.
• Xabi Alonso returns to Anfield as Madrid boss after six straight wins.
• Salah chasing goal number 251 in a revived Liverpool attack.
• Mbappé in red-hot form, leading the Champions League scoring charts.

Liverpool finally ended their Premier League slump with a 2-0 win over Aston Villa on Saturday. It wasn’t vintage football, but it was enough to lift the tension around Arne Slot. Mohamed Salah’s 250th goal in red shirts set the tone, and Ryan Gravenberch sealed the win with a deflected strike. That’s the energy Anfield needed heading into this one. Still, it’s hard to ignore the inconsistency. Two wins from their last eight across competitions is a worrying sign, but at home in Europe? That’s a different story. The Reds have now won 15 straight group or league-phase matches at Anfield. Fortress mentality, reloaded.

Slot’s side has struggled with injuries: Alisson, Frimpong, and Isak all sidelined, but the core remains intact. Expect Mamardashvili in goal after a confidence-boosting clean sheet, while Mac Allister and Robertson anchor a rebalanced lineup. “We needed that win,” Slot admitted post-match, visibly relieved. Can he really turn things around against the 15-time champions? Maybe. It’s Anfield after all, where logic sometimes takes a night off.

Over in Spain, Xabi Alonso’s Real Madrid just keep rolling. Saturday’s 4-0 demolition of Valencia was their 13th win in 14 games. Mbappé’s brace reminded everyone why he’s Europe’s deadliest traveller, more than half of his 60 Champions League goals have come away from home. Add in Bellingham’s unstoppable midfield runs and a rock-solid defense, and you’ve got a machine that barely stalls. The only recent blemish? A 5-2 derby loss to Atlético. Apart from that, Los Blancos have been flawless. Alonso’s calm leadership has turned chaos into controlled dominance. That’s a bold move, but maybe the right one.

Still, Real have their own problems. Rudiger, Carvajal, and Alaba are out, forcing some improvisation at the back. Could that open the door for Liverpool’s attack? Possibly. But it’s also hard to bet against this Madrid side, given their habit of thriving when it matters. With Mbappé, Vinícius Jr., and Bellingham in full flight, they have firepower to silence any crowd. And if you’ve followed the Champions League Stats lately, you’ll know one truth: Madrid rarely stay quiet for long.